Steve Coogan, an arrogant actor with low self-esteem and a complicated love life, is playing the eponymous role in an adaptation of “The Life and Opinions of Tristram Shandy, Gentleman” being filmed at a stately home. He constantly spars with actor Rob Brydon, who is playing Uncle Toby and believes his role to be of equal importance to Coogan’s.

A young doctor in a US hospital administers a powerful and untested cocktail of drugs to a coma victim. But instead of curing him, it triggers a powerful “out-of-body” experience and enables the patient – a depraved and dangerous loner – to inhabit other people’s bodies and, through them, take revenge on the bullying medical students who were accidentally responsible for his condition.